Two sample MR report
THEMIS2_Mature NK T Cell against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | -0.0085100 | 0.0556675 | 0.8859006 |
| Weighted median | 6 | -0.0119932 | 0.0061847 | 0.0524799 |
| Inverse variance weighted | 6 | -0.0124916 | 0.0052476 | 0.0172920 |
| Simple mode | 6 | -0.0117206 | 0.0083278 | 0.2183290 |
| Weighted mode | 6 | -0.0118158 | 0.0081851 | 0.2084580 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1612538 | 4 | 0.9969192 |
| Inverse variance weighted | 0.1664155 | 5 | 0.9994336 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0037723 | 0.0525061 | 0.9461746 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001172 | 0 | TRUE | 0.3031865 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
